CO2 Modulation in Endovascular Thrombectomy for Acute Ischemic Stroke
Recruiting
Phase 2
Interventional Study
Ischemic Stroke, Acute
Thrombectomy
Anesthesia, General
Cerebrovascular Circulation
Carbon Dioxide
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 50 (estimated)
- Sponsor
- University Hospital, Clermont-Ferrand · Other
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About This Trial
Acute ischemic stroke due to large vessel occlusion is responsible of cerebral blood flow impairment with a progressive and extensive ischemic process. Cerebral collateral circulation may preserve an ischemic penumbra that could recover providing timely reperfusion of the occluded vessel. Mechanical thrombectomy is the standard of care for anterior circulation large vessel reperfusion. Strategy to…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
• Large vessel occlusion anterior circulation stroke (terminal carotid artery and/or middle cerebral artery M1-M2 segment) eligible to mechanical thrombectomy under general anesthesia
Exclusion Criteria :
* Active smoker
* Chronic respiratory failure with ambulatory oxygen sup…
Contacts