Midodrine for the Early Liberation of Vasopressor Support in the ICU (LIBERATE Multi-Site)
Recruiting
Phase 4
Interventional Study
Vasoplegia
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 870 (estimated)
- Sponsor
- University of Alberta · Other
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About This Trial
Vasopressors are medications that are given intravenously to increase the blood pressure of patients with illnesses that cause dangerous blood pressure drops. When a doctor prescribes a vasopressor, they ask that the dose be adjusted to achieve a specific blood pressure. This kind of medical support with intravenous (IV) vasopressors are usual treatments in intensive care unit (ICU) settings. Oral…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age \> 18 years
* Ongoing vasopressor support
* Decreasing vasopressor dose(s)
Exclusion Criteria:
* Greater than 24 hours from peak vasopressor dose
* Contraindication to enteral medications
* Previously received midodrine in last 7 days
* Expected death or anticipated with…
Contacts