Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia
Recruiting
N/A
Interventional Study
Schizophrenia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 40
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 75 (estimated)
- Sponsor
- Fabio Ferrarelli · Other
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About This Trial
This study will investigate the effects of intermittent Theta Burst Stimulation (iTBS) on natural oscillatory frequency of the dorsolateral prefrontal cortex (DLPFC) and working memory in early-course schizophrenia (EC-SCZ). Transcranial magnetic stimulation (TMS) will be used to evoke oscillatory activity, and EEG will record the responses of EC-SCZ participants. A working memory task will also b…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. ages 18-40 years
2. DSM diagnoses of Schizophrenia Spectrum Axis I disorders
3. a duration of less than three years from beginning of psychosis, defined by report of symptoms and/or history of treatment, based on clinical guidelines employed in our UPMC psychoses clinics in P…
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