Characterization of Humoral and Cellular Immune Responses Elicited by Influenza Vaccination in Healthy Adults

Recruiting Phase 4 Interventional Study
Influenza, Human
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Basic Science
Participants needed
700 (estimated)
Sponsor
University of Pennsylvania · Other
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About This Trial
Cellular and humoral immune responses before and after seasonal influenza vaccination will be assessed. Each year, up to 100 participants will be enrolled. To study age-specific differences in immune responses, participants with various years of birth will be enrolled. The investigators hypothesize that humans with different birth years will mount antibody and cellular responses of different speci…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Provision of signed and dated informed consent form 2. Stated willingness to comply with all study procedures and availability for all study visits 3. Aged 18 years and older 4. In good health based on self-reported medical conditions via an online survey Exclusion Criteria:…
Contacts

Scott Hensley, PhD

215-573-3756

hensley@pennmedicine.upenn.edu

CONTACT

Elizabeth Drapeau, PhD

215-573-3756

elizabeth.troisi@pennmedicine.upenn.edu

CONTACT