Muscle Blood Flow Regulation in HFpEF
Recruiting
N/A
Interventional Study
HFpEF
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 35 (estimated)
- Sponsor
- VA Office of Research and Development · Federal
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About This Trial
Heart failure with preserved ejection (HFpEF) disproportionately affects Veterans and is the number one reason for hospital discharge in the VA Health Care System. Exercise intolerance is a common complication experienced by patients with HFpEF, perpetuating physical inactivity and accelerating disease progression. This research proposal aims to elucidate mechanisms responsible for inadequate skel…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 18 years or older and able to give written informed consent
* New York Heart Association (NYHA) functional class II or III
* Left Ventricular Ejection Fraction (LVEF) \> 50%
* Plasma Brain Natriuretic Peptide (BNP) \>200 pg/mL or NT-proBNP 400 pg/mL at enrollment
Exclusio…
Contacts