Radiotherapy vs Observation for Post Chemotherapy Residual Mass in Advanced Seminoma

Recruiting N/A Interventional Study
Seminoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 80
Sex
Male
Study type
Interventional
Purpose
Treatment
Participants needed
74 (estimated)
Sponsor
Tata Memorial Centre · Other
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About This Trial
Testicular tumors account for 1% of all cancers in males and germ cell tumors comprise 95% of all testicular cancers. Seminomas consist of around 50% of cases. However,adequate information is not there as 60- 80% residual disease is seen even after with the standard management of chemotherapy. With the advent of functional imaging there was hope that it could aid in more accurately targeting thes…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Histological diagnosis of classical seminoma 2. Primary site - testis, mediastinum or retroperitoneum 3. Stage IIB-IIIC (AJCC 8th edition) 4. Age\>18 years 5. Karnofsky Performance Status at least 70 6. A response assessment FDG PETCT scan done at least twelve weeks after the…
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