Functional Magnetic Resonance Imaging in Patients With Obstructive Sleep Apnea Syndrome
Recruiting
N/A
Interventional Study
Obstructive Sleep Apnea Syndrome
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 75
- Sex
- Any
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 70 (estimated)
- Sponsor
- CHU de Reims · Other
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About This Trial
The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration. UA collapse does not occur during wakefulness, hence arousal-dependent compensation. Experimental inspiratory loading in normal subjects elicits respiratory-related cortical activity during wake…
Trial Locations
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Eligibility Criteria
Inclusion criteria :
1. OSAS patients
* severe OSAS with an Apnea-Hypopnea Index (AHI) \> 30/h
* without CPAP treatment
2. Non-OSAS patients
* absence of OSAS (AHI \< 15/h and absence of excessive daytime sleepiness with Epworth score \<11)
Non-inclusion criteria :
* \< 18 years old
* …
Contacts