Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor

Recruiting N/A Interventional Study
Laryngeal Dystonia Spasmodic Dysphonia Tremor Dystonia
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 80
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
120 (estimated)
Sponsor
Massachusetts Eye and Ear Infirmary · Other
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About This Trial

The goals of this project are 1) to determine the incidence of neurological voice disorders in patients with dystonia and essential tremor undergoing deep brain stimulation (DBS), 2) investigate the neuroimaging and intracranial neurophysiology correlates of voice dysfunction in these subjects, and subsequently 3) determine the effects of DBS on voice function.

Trial Locations
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Eligibility Criteria
Inclusion 1. Clinical indications to proceed with DBS implantation, as determined by the clinical multidisciplinary movement disorders board, including: a) definitive diagnosis of essential tremor or dystonia, b) medically refractory disease, c) adequate performance on neuropsychological evaluation…
Contacts

Kristina Simonyan, MD, PhD

617-573-6016

simonyan_lab@meei.harvard.edu

CONTACT