18F-DCFPyL Imaging for Localized Prostate Cancer Treatment
18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy
Recruiting
Phase 2
Interventional Study
Localized Prostate Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 120
- Sex
- Male
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 130 (estimated)
- Sponsor
- National Cancer Institute (NCI) · NIH
Who this trial is looking for
This trial is looking for men 18 and older who have localized prostate cancer and plan to receive specific radiation therapy. Participants will undergo imaging scans and provide health information during the study.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with localized prostate cancer.
- I plan to receive stereotactic body radiation therapy.
- I am at least 18 years old.
- I understand and am willing to sign consent.
- I agree to use birth control during the study.
- I have at least one MRI-detected localized prostate cancer.
- I have a performance status of 2 or lower.
- If I have HIV, I am on effective treatment with an undetectable viral load.
You may not be able to join if
- I have received prior androgen deprivation therapy.
- I have evidence of tumor spread beyond the prostate.
- I weigh more than 350 lbs.
- I have conditions that may interfere with the study.
- I have contraindications to radiation therapy.
- I am scheduled for pelvic nodal irradiation.
- I have a serum creatinine level above the normal range.
- I have received prior surgery for prostate cancer.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
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About This Trial
Background:
Identifying medium- and high-risk prostate cancer early may allow for treatments to work. But identification can be hard. Researchers want to see if a radiotracer used during PET scans can help.
Objective:
To test how an imaging agent called 18F-DCFPyL detects response to standard prostate cancer treatment.
Eligibility:
People ages 18 and older with newly diagnosed prostate cancer…
Trial Locations
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Eligibility Criteria
* INCLUSION CRITERIA:
* Biopsy proven localized prostate cancer in whom stereotactic body radiation treatment (SBRT) with or without neoadjuvant androgen deprivation therapy (ADT) is planned for definitive management (NIH laboratory of pathology confirmation is not required).
* Must have at least 1 …
Contacts