oGVHD After Bone Marrow Transplantation: a Territory-wide Cohort
Recruiting
Observational Study
Graft Vs Host Disease
Haematological Malignancy
Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 500 (estimated)
- Sponsor
- The University of Hong Kong · Other
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About This Trial
Allogeneic Haematopoietic stem cell transplantation (HSCT) is an effective treatment for all array of blood or blood-producing organ disorders. Graft-versus-host-disease (GVHD) occurs as a result of an overactive immunological system against normal host tissues. It can happen in the liver, skin, mucosal surface of the eye, gastrointestinal tract, and genitalia.
Ocular GVHD occurs in 30-70% of pat…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patient aged 18 or above
* Underwent allogeneic HSCT in QMH in the two-year recruitment period
Exclusion Criteria:
* Underwent autologous HSCT
* Patient unable to attend follow-up visits
Family Control Subjects The research team will invite an accompanying family member to …