Imaging the Interplay Between Axonal Damage and Repair in Multiple Sclerosis
Recruiting
Observational Study
Multiple Sclerosis (MS)
Relapsing-remitting Multiple Sclerosis (RRMS)
Secondary-progressive Multiple Sclerosis (SPMS)
Primary Progressive Multiple Sclerosis (PPMS)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Study type
- Observational
- Participants needed
- 300 (estimated)
- Sponsor
- University Hospital, Basel, Switzerland · Other
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About This Trial
This project is to: 1. Quantify differences in axonal integrity and organization in aMS versus naPMS patients. 2. Quantify changes in axonal integrity and organization in aMS versus naPMS patients over a two-year period. 3. Validate the combination of imaging parameters that best differentiate aMS versus naPMS patients using histopathology.
Trial Locations
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Eligibility Criteria
Inclusion Criteria for patients:
* Patients may be diagnosed with:
1. active RRMS (n=100): Relapsing-remitting course and \> 1 clinical relapse and/or signs of MRI activity (\> 1 Gd enhancing lesion) during the last year before study enrollment.
2. non-active PMS (n=100): Progressive course (P…
Contacts