PROfiling Based Endometrial Cancer Adjuvant Therapy
Recruiting
N/A
Interventional Study
Endometrial Cancer Stage I
Endometrial Cancer Stage II
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 75
- Sex
- Female
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 590 (estimated)
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University · Other
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About This Trial
This is a prospective, multicenter, randomized phase III trial among women with endometrioid adenocarcinoma with high-intermediate and intermediate risk features to investigate the role of integrated genomic-pathologic classification to determine if participants should receive no adjuvant therapy, vaginal brachytherapy, external beam radiotherapy or chemo-radiation therapy based on molecular featu…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Surgery consisting of a total abdominal or laparoscopic hysterectomy, bilateral salpingectomy, pelvic lymphadenectomy or sentinel lymph node mapping and dissection, with or without para-aortic lymphadenectomy, oophorectomy
2. Histologically confirmed endometrioid type endomet…
Contacts