Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response

Recruiting N/A Interventional Study
Phantom Limb Pain
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
290 (estimated)
Sponsor
Spaulding Rehabilitation Hospital · Other
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About This Trial
The investigators have designed a pragmatic trial of home-based transcranial direct current stimulation (tDCS) for phantom limb pain (PLP), the PLP-EVEREST trial (PLP-EffectiVEness pRagmatic Stimulation Trial) to test a portable device that would reach underrepresented populations and would validate this therapy in a more pragmatic setting. Subjects will be randomized to home-based tDCS of the pri…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age - older than 18 years 2. Limb amputation 3. Patients who experience PLP regularly (at least once a week) 4. Pain not attributable to other causes, such as peripheral inflammation 5. Current chronic pain as defined by an average pain of at least 4 on the numeric rating sca…
Contacts

Felipe Fregni, MD, PhD, MPH, MMSc

617-952-6158

ffregni@partners.org

CONTACT

Kevin Pacheco-Barrios, MS, MSc, MPH

617-952-6195

kpachecobarrios@mgh.harvard.edu

CONTACT