Cardiopulmonary Bypass Induced Red Blood Cell Lysis
Recruiting
Observational Study
Cardiopulmonary Bypass
Cardiac Surgery
Kidney Injury, Acute
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 88
- Sex
- Any
- Study type
- Observational
- Participants needed
- 150 (estimated)
- Sponsor
- University of Maryland, Baltimore · Other
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About This Trial
Studying the dynamics of red blood cell lysis, pfH, protective proteins and organ injury, limits will be set for safe levels of pfH following the use of CPB. These results will be compared to existing laboratory-based methods for determining red blood cell damage to predict CPB assist device safety. Further, results from the studies described in this proposal will help develop therapeutic strategi…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Admitted to UMMC for cardiac procedure
* Age: \>/=18 y.o TO 88 y.o.
* Undergoing CPB \>1hr for the following surgeries (a) complex cardiac surgery (b) heart valve replacement surgery OR (c) CABG surgery.
Exclusion Criteria:
* Pregnant
* Non English speaking
* Unable to conse…
Contacts