Immune Modulation by Exosomes in COVID-19

Recruiting Observational Study
COVID-19 Critical Illness Hypercytokinemia Lung Fibrosis
Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 90
Sex
Any
Study type
Observational
Participants needed
40 (estimated)
Sponsor
University of Ulm · Other
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About This Trial

Following whole blood stimulation with mesenchymal stem cell derived exosomes, immune phenotype, cytokine release and mRNA expression patterns from critically ill patients with COVID-19 will be determined.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Critically ill COVID-19 patients with lung dysfunction * COVID-19 WHO severity degree \>= 4, ARDS (WHO Definition 13 March 2020) * Body weight \> 50 kg * Informed consent Exclusion Criteria: * Pregnant or breast feeding women
Contacts

Manfred Weiss, MD

+49(0)731500

manfred.weiss@uniklinik-ulm.de

CONTACT

Marion Schneider, PhD

+49(0)731500

marion.schneider@uni-ulm.de

CONTACT