Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Recruiting Early Phase 1 Interventional Study
Obesity Vasodilation Healthy
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 45
Sex
Any
Trial phase
Early Phase 1
Study type
Interventional
Purpose
Basic Science
Participants needed
72 (estimated)
Sponsor
University of Missouri-Columbia · Other
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About This Trial

The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * BMI \>18 kg/m2 Exclusion Criteria: * Pregnancy, breastfeeding * Diagnosed sleep apnea or AHI \>10 events/hr * Current smoking/Nicotine use * Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy * Nerve/neurologic disease * Cardiova…
Contacts

Jacqueline K Limberg, Ph.D.

5738822544

limbergj@missouri.edu

CONTACT