ProSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors (START-TKI)

Recruiting Observational Study
Non Small Cell Lung Cancer Liquid Biopsy Tyrosine Kinase Inhibitor
No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
1,300 (estimated)
Sponsor
Erasmus Medical Center · Other
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About This Trial

The study is perfomed with adult patients with non-small cell lung cancer treated with tyrosine kinase inhibitor. The objective is to collect repeated samples of blood from patients (starting) on a tyrosine kinase inhibitor, for liquid mutation testing, and pharmacokinetic analysis.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Able to understand the written informed and able to give informed consent * Locally advanced or metastatic NSCLC with oncogenic driver mutation * Treatment with TKI according to standard of care Exclusion Criteria: * Unable to draw blood for study purposes
Contacts

Anne-Marie Dingemans, MD, PhD

+31107040704

a.dingemans@erasmusmc.nl

CONTACT