No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
13 – 24
Sex
Any
Study type
Observational
Participants needed
10 (estimated)
Sponsor
University of California, Los Angeles · Other
Who this trial is looking for
This trial is looking for teens and young adults aged 13-24 with restrictive-type anorexia nervosa who are in the hospital for feeding. Participants will have extra blood and urine tests during their stay to help researchers understand hormone levels and urine output.
Are You a Good Fit for This Trial?
You may be able to join if
I am aged 13-24 years
I have been diagnosed with restrictive-type anorexia nervosa
I am in the hospital for nutritional support
I urinate more than 4 cc/kg/day
I am male or female
You may not be able to join if
I am currently under a 5150 hold
I am taking anti-depressant, anti-psychotic, or anticonvulsant medications
I have been hospitalized in the past 6 months
I have a metabolic disorder not related to anorexia
I am pregnant
I have been on tube feeds after day 2 of hospitalization
More than 10% of my nutritional needs come from supplemental feeds
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Patients with restrictive-type anorexia nervosa who are admitted to the hospital for feeding often urinate excessive amounts. Others have changes in the way that they handle acid and base. These issues prolong hospitalizations. Current data suggest that one hormone--named secretin--may control both urine output and how the body handles acid and base. This study will evaluate whether secretin level…
Patients with restrictive-type anorexia nervosa who are admitted to the hospital for feeding often urinate excessive amounts. Others have changes in the way that they handle acid and base. These issues prolong hospitalizations. Current data suggest that one hormone--named secretin--may control both urine output and how the body handles acid and base. This study will evaluate whether secretin levels are different in anorexic patients who urinate an excessive amount compared to those who urinate normal amounts. For this study, patients will have one extra blood draw before and after one meal during their hospitalization. The blood draw before the meal coincides with a standard of care blood draw. Also after the meal, subjects will be asked to provide one extra urine sample. Information from subject's medical records will also be used.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Group 1:
* male and female patients
* age 13-24 years
* diagnosis of restrictive-type anorexia nervosa
* hospitalization for nutritional support
* \>4 cc/kg/day of urine output (a.k.a. "fluid dumpers"; n=5)
* Group 2:
* male and female patients
* age 13-24 year…
Inclusion Criteria:
* Group 1:
* male and female patients
* age 13-24 years
* diagnosis of restrictive-type anorexia nervosa
* hospitalization for nutritional support
* \>4 cc/kg/day of urine output (a.k.a. "fluid dumpers"; n=5)
* Group 2:
* male and female patients
* age 13-24 years
* diagnosis of restrictive-type anorexia nervosa
* hospitalization for nutritional support
* \<2 cc/kg/d of urine output (a.k.a. "non-dumpers"; n=5)
Exclusion Criteria:
* 5150 hold
* Anti-depressant, anti-psychotic, or anticonvulsant medications
* Previous hospitalization within the past 6 months
* Underlying metabolic disorder not related to anorexia nervosa (including chronic kidney disease, renal tubular disorders, and underlying endocrine disorders)
* Pregnancy
* NG or G-tube feeds after day 2 of hospitalization
* \> 10% of nutritional needs from supplemental feeds
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