Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar Depression
Recruiting
N/A
Interventional Study
Anhedonia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 50
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 45 (estimated)
- Sponsor
- The University of Texas Health Science Center, Houston · Other
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About This Trial
The purpose of this study is to investigate whether transcranial direct-current stimulation (tDCS) will engage reward-related brain circuitry, more specifically the uncinate fasciculus (UF) tract, which connects the orbitofrontal cortex (OFC) and nucleus accumbens (NAcc) regions. Also to evaluate whether the changes in the fractional anisotropy (FA) of the UF tract are associated with changes of c…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* diagnosis of Bipolar Disorder and clinically significant anhedonia
* mild symptoms of depression
Exclusion Criteria:
* substance abuse/dependence and any use of drugs (except alcohol or nicotine) in the previous month of the baseline assessment
* participants with personalit…
Contacts