A Study of ImmunoPet Imaging Using 89Zr-DFO-REGN5054 in Adult Participants With Solid Cancers Treated With Cemiplimab
Recruiting
Phase 1
Interventional Study
Advanced Solid Tumor
Metastatic Solid Tumor
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 50 (estimated)
- Sponsor
- Regeneron Pharmaceuticals · Industry
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About This Trial
This study is researching an experimental drug called 89Zr-DFO-REGN5054 and cemiplimab. The study is focused on patients with a type of cancer that can be potentially imaged using 89Zr-DFO-REGN5054 and show special tumor features that may be important to the way the immune system fights cancer.
The aim of the study is to study the safety and tolerability (how the body reacts to the drug) of the i…
Trial Locations
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Eligibility Criteria
Key Inclusion Criteria:
* Advanced or metastatic solid tumors that may respond to anti-programmed cell death 1 (PD-1) immunotherapy
* Measurable disease according to Response Evaluation Criteria in Solid Tumours (RECIST) 1.1 criteria
* Eastern Cooperative Oncology Group (ECOG) performance status of…
Contacts