Mucosal IgE to Improve Diagnosis of Food Allergy and Food Hypersensitivity

Recruiting N/A Interventional Study
Food Allergy Food Hypersensitivity
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
115 (estimated)
Sponsor
University of Erlangen-Nürnberg Medical School · Other
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About This Trial
Aim of the study is to improve the diagnosis of food allergy and hypersensitivity. Intestinal homogenates will be used to determine total IgE, specific IgE, tryptase, histamine and inflammation parameters (IFNgamma, TNFalpha). These data will be correlated with serum values and disease status. In addition, organoids from duodenal tissue will be isolated and cultured in vitro and stimulated with th…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * informed consent * patients with suspected food allergy or hypersensitivity * healthy controls with indications for endoscopic diagnostics, e.g. tumour history within the family, exclusion of gastritis Exclusion Criteria: * pregnant person
Contacts

Yurdagül Zopf, Prof

+4991318545218

yurdaguel.zopf@uk-erlangen.de

CONTACT

Walburga Dieterich, Dr

+4991318535128

walburga.dieterich@uk-erlangen.de

CONTACT