Selective Internal Radiation Therapy and Capecitabine (Chemotherapy) Treatment for Liver Cancer

Inclusion Criteria: 1. Age \> 18 years-old, 2. ECOG Performance Status \<2, 3. Histologically-proven ICC, 4. No previous treatment for ICC, 5. Tumour deemed resectable by a hepatobiliary surgeon, validated by a Surgical Review Board, 6. Significant risk of close margins, defined as: 1. Resection margin predicted by the surgeon \<1 cm 2. Tumour \>5 cm 3. Multifocal lesion deemed resectable, validated by a Surgical Review Board 7. Registration with a social security scheme, 8. Patient information and signature of informed consent or legal representative. Non-inclusion Criteria: 1. Severe fibrosis (F3) ou cirrhosis (F4), 2. Inadequate haematological, hepatic, renal and coagulation functions: 1. Haemoglobin ≤ 8,5 g/dl 2. Neutrophils \< 1,5 Giga/L 3. Platelets \< 60 Giga/L 4. Bilirubin \> 34 µmol/L 5. ASAT/ALAT \> 5 x ULN 6. Creatinine clearance \< 30 ml/min (MDRD) 7. TP et INR \> 2,3 ULN 8. TCA \> 1,5 x ULN 3. Uracil blood level \>16 ng/mL, 4. Respiratory insufficiency, 5. Comorbidity precluding surgical resection, such as severe heart disease, 6. Presence of microvacuolar steatosis \> 60% or regenerative nodular hyperplasia, for patients for whom a major hepatectomy is planned, 7. Contraindication to hepatic artery catheterization (vascular abnormalities, bleeding diathesis), 8. Previous chemotherapy (including for another cancer), 9. Previous abdominal (supra-mesocolic) radiotherapy (including for another cancer), 10. Other invasive malignancies, 11. Patient participate to an interventional study that tests another medical intervention before surgery, 12. Pregnant woman or likely to be or breastfeeding, or male or female patients of reproductive potential without effective contraception from screening to 30 days after the end of the treatment adjuvant, 13. Minors, individual deprived of liberty, or under any kind of guardianship, 14. Patients unable to submit to medical follow-up of the study for social, medical or psychological reasons. Exclusion Criteria: 1. Pulmonary shunt with dose \>30Gy, 2. Digestive shunting, non-correctible by interventional radiology, 3. Absence of fixation of MAA in the tumour.