Valacyclovir for Pain Management of Acute Apical Abscesses
Valacyclovir in Pain Management of Acute Apical Abscesses
Recruiting
Phase 2
Interventional Study
Acute Apical Abscess
Pain, Acute
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- University of California, San Francisco · Other
Who this trial is looking for
This trial is looking for adults with severe tooth pain caused by an acute apical abscess. Participants will be treated and monitored for pain relief and healing over time.
Are You a Good Fit for This Trial?
You may be able to join if
- I am at least 18 years old
- I am generally healthy
- I have severe tooth pain (pain level higher than 4)
- I have been diagnosed with pulp necrosis and an acute apical abscess
- I have signs of apical disease on X-rays
- I agree to have treatment for my tooth condition
You may not be able to join if
- I smoke more than 10 cigarettes per day
- I have tooth resorption
- I have marginal periodontitis
- I am pregnant or nursing
- I am allergic to amoxicillin or valacyclovir
- I have teeth with unusual anatomy
- I am currently taking antibiotics or antiviral medications
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The Virus in Endodontics (VE) phase I pilot study for preoperative pain will be analyzed and adjusted for the Phase II clinical trial. The Phase II clinical trial on preoperative pain, postoperative pain, and clinical healing will involve 250 patients. Patients will be recruited from the same pool of participants as the Phase II clinical trial. Preoperative cone beam computed tomography (CBCT) sca…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patient must be ≥ 18-year-old
* Patient must be systemically healthy; American Society of Anesthesiologists (ASA) Class I or II
* Patient must exhibit clinical evidence of pulp necrosis and acute apical abscess
* Patient must present with radiographic
* signs of apical disease…
Contacts