No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
19 and older
Sex
Any
Study type
Observational
Participants needed
150 (estimated)
Sponsor
Chonnam National University Hospital · Other
Who this trial is looking for
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To compare clinical outcomes of myocardial infarction with non-obstructive coronary arteries (MINOCA) according to the coronary microvascular dysfunction (CMD), evaluated by optical coherence tomography (OCT), invasive and non-invasive coronary physiologic assessment.
Trial Locations
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Facility
City
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Status
Eligibility Criteria
Inclusion Criteria:
* Subject with age ≥19 years and acute myocardial infarction
* Rise and/or fall of cardiac troponin with one level \>99 percentile plus ischemic signs/symptoms
* Subject with non-obstructive coronary arteries
* \<50% diameter stenosis or
* fractional flow reserve (FF…
Inclusion Criteria:
* Subject with age ≥19 years and acute myocardial infarction
* Rise and/or fall of cardiac troponin with one level \>99 percentile plus ischemic signs/symptoms
* Subject with non-obstructive coronary arteries
* \<50% diameter stenosis or
* fractional flow reserve (FFR) \>0.80 ③ Subject without previous history of coronary artery disease
* Subject who performed invasive coronary angiography within 24 hours after presentation ⑤ Subject who eligible for invasive and non-invasive coronary physiologic assessment
Exclusion Criteria:
* Subject with obstructive coronary arteries
* Subject with alternate diagnosis including sepsis, pulmonary embolism, myocarditis, Takotsubo syndrome, spontaneous coronary dissection, and other cardiomyopathies.
* Subject with cardiogenic shock or cardiac arrest ④ Subject who has non-cardiac co-morbid conditions with life expectancy \<1 year ⑤ Subject or lactating women ⑥ Subject unable to provide consent
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