Pain Control After Urethra Surgery
Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty
Recruiting
Phase 3
Interventional Study
Urethral Stricture, Male
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Male
- Trial phase
- Phase 3
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- University of California, San Francisco · Other
Who this trial is looking for
This trial is looking for men aged 18 or older who are having surgery to fix a narrowing in the urethra using tissue from the inside of the cheek. Participants will receive different methods of pain relief during and after the surgery to see which one works best.
Are You a Good Fit for This Trial?
You may be able to join if
- I am a man aged 18 or older
- I am having surgery for a urethral stricture
- I can give my consent to participate
You may not be able to join if
- I have been taking painkillers regularly
- I have chronic pain
- I have had this urethra surgery before
- I am part of a vulnerable population
- I have kidney problems or allergies to NSAIDs
- I have liver problems or allergies to Tylenol
- I have an allergy to local anesthetics
- I have an allergy to Peridex or Magic Mouthwash
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including graft site closure have been explored. Despite the frequency of this clinical scenario there is no established best practice for peri-operative pain management in this patient population. In addition to…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Men, age 18 or older
* Undergoing anterior urethroplasty with buccal grafting
* Able to consent
Exclusion Criteria:
* Taking chronic opiates for pain
* Diagnosis of chronic pain
* Prior buccal urethroplasty
* Vulnerable population (e.g. prisoner)
* Renal dysfunction or aller…
Contacts