Cytokine Expression in Psoriasis Patients With and Without Joint Involvement
Recruiting
N/A
Interventional Study
Psoriasis
Psoriatic Arthritis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 100
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 40 (estimated)
- Sponsor
- Poitiers University Hospital · Other
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About This Trial
The objective of the resarch is to study the cytokine profile of patients with psoriatic arthritis and psoriasis in order to better understand the pathophysiology of the disease and the contribution of cytokines to the presence or absence of joint involvement. This research will compare cytokines levels in sera, in PBMC culture after LPS or CD3/CD28 agonist antibodies, and in skin biopsy.
Trial Locations
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Eligibility Criteria
Inclusion criteria:
* For psoriasis patients :
* Age over 18 years old
* Signed informed consent
* 5 year old psoriasis at least
* At least one skin lesion over 2 cm
* Without any articular symptoms
* Without any DMARDs
* Without anticoagulant treatments or coagulation disease
* Wi…
Contacts