Targeted Optical Biopsy for Local Rectal Scars in Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy

Recruiting N/A Interventional Study
Rectal Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 80
Sex
Any
Study type
Interventional
Purpose
Diagnostic
Participants needed
68 (estimated)
Sponsor
Nanfang Hospital, Southern Medical University · Other
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About This Trial
Currently, low concordance (36%) is found between clinical complete response and pathologic complete response in patients with rectal cancer after neoadjuvant chemoradiotherapy. Probe-based confocal laser endoscopy (pCLE) provides a promising targeted optical biopsy to evaluate the response to neoadjuvant chemoradiotherapy. The aim of this study is to investigate whether pCLE-targeted optical biop…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age from over 18 to under 80 years 2. American Society of Anesthesiology(ASA) score class I,II,or III 3. Locally advanced rectal cancer 4. Patient has completed standard neoadjuvant therapy 5. Expected surgical resection 6. Written informed consent Exclusion Criteria: 1. Pr…
Contacts

Jun Yan, M.D., Ph.D.

086-13825066546

yanjunfudan@163.com

CONTACT