Expanded Haploidentical Natural Killer Cells as Consolidation Strategy for Children/Young Adults With AML

Recruiting Phase 1 Phase 2 Interventional Study
Acute Myeloid Leukemia
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
6 Months – 21
Sex
Any
Trial phase
Phase 1/2
Study type
Interventional
Purpose
Treatment
Participants needed
15 (estimated)
Sponsor
Belarusian Research Center for Pediatric Oncology, Hematology and Immunology · Other
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About This Trial

The purpose of this study is to estimate the efficacy of immunotherapy with ex vivo expanded haploidentical NK cells as consolidation therapy for children/young adults with intermediate risk AML.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: Patients: * primary intermediate risk AML in molecular complete remission; * primary high risk AML in molecular complete remission awaiting unrelated HSCT; * Karnofsky or Lansky performance scale greater or equal to 70; * written informed consent. Donors: * haploidentical fam…
Contacts

Tatsiana Shman, PhD

+375296341853

shman@oncology.by

CONTACT

Mariya Naumovich, MD

+375293563846

mariyanaumovich@gmail.com

CONTACT