Study of PAT in Patients With Solid Tumor Cancers

Recruiting Phase 1 Interventional Study
Metastasis Solid Tumor
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
21 (estimated)
Sponsor
Masonic Cancer Center, University of Minnesota · Other
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About This Trial

This is a single center Phase I study with extension of peptide alarm therapy (PAT) administered by intratumoral (IT) injection during the 1st course of a standard of care intravenous PD-1/PD-L1 inhibitor for the treatment of locally advanced or metastatic solid tumor cancers that has failed to be controlled after one or more prior therapies including a previous PD-1/PD-L1 inhibitor

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Must be seropositive for CMV and EBV. * Must have at least one HLA-A\*0201 allele. This screening can be performed after determining CMV and EBV seropositivity is established or, if available, from the results of previous tumor profiling by any CLIA-certified lab (i.e. Caris, …
Contacts

Cancer Center Clinical Trials Office

612 624 2620

ccinfo@umn.edu

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