Genetics of the Acute Response to Oral Semaglutide
Recruiting
N/A
Interventional Study
PreDiabetes
Prediabetic State
Obesity
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 1,000 (estimated)
- Sponsor
- Medical University of Bialystok · Other
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About This Trial
The study aims to investigate the genetic basis of the response to short-term (3 months) orally administered semaglutide treatment, in terms of improving metabolic parameters, including the hormonal response to a standardized meal, and changes in body composition and liver steatosis. In the study, parameters such as fasting and 2-hour glucose during OGTT, HbA1c, body fat mass, body weight, total c…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Informed consent was given before any study-related action on the subject.
* Age: 18-65 years old
* Body mass index (BMI) \>30 kg/m2 or \>27 kg/m2 when accompanied by prediabetes, diagnosed according to the criteria of the American Diabetes Association
Exclusion Criteria:
* …
Contacts