Spinal Cord Stimulation for Spondylosis and Stenosis
Recording of Intraoperative Spinal Cord Stimulation and Monitoring
Recruiting
N/AInterventional Study
Cervical StenosisDisk, HerniatedSpondylosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
150 (estimated)
Sponsor
University of California, Los Angeles · Other
Who this trial is looking for
This trial is looking for patients who are having brain or spinal cord surgery and can use spinal monitoring. Participants will receive spinal cord stimulation during their surgery to see how it affects their breathing.
Are You a Good Fit for This Trial?
You may be able to join if
I am having brain or spinal cord surgery.
I can use spinal neuromonitoring.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery…
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.
Exclusion Criteria:
* none
Inclusion Criteria:
* Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.
Exclusion Criteria:
* none
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