Testing Effects of Melatonin on Uterine Contractions in Women

Recruiting N/A Interventional Study
Pregnant Women
Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 35
Sex
Female
Study type
Interventional
Purpose
Basic Science
Participants needed
120 (estimated)
Sponsor
Brigham and Women's Hospital · Other
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About This Trial
The study will extend recent discoveries that have been made in basic human physiology related to responses melatonin and uterine contractions in late- or full-term pregnant women. The basic physiology work has been conducted in in vitro models of the human myometrium characterizing its responses to melatonin, and in pilot in vivo studies correlating the number of uterine contractions with melaton…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * nulliparity, age between 18 and 35, * BMI\<36 pre-pregnancy, * ≥38 weeks of pregnancy with a single fetus at time of study. Exclusion Criteria: * color blind; * prescription drugs affecting sleep, melatonin, and/or circadian rhythms (e.g., beta blockers, non-steroidal anti-i…
Contacts

Elizabeth B Klerman, MD PhD

617-643-2424

ebklerman@hms.harvard.edu

CONTACT

Shadab A Rahman, PhD

617-525-8830

sarahman@rics.bwh.harvard.edu

CONTACT