Neuromodulation of the Fear Extinction Circuit Using Temporally and Anatomically Specific TMS in Humans
Recruiting
N/A
Interventional Study
PTSD
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 250 (estimated)
- Sponsor
- The University of Texas Health Science Center, Houston · Other
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About This Trial
This study aims to explore the mechanisms of how transcranial magnetic stimulation (TMS) impacts fear circuits. The overarching objectives are to understand how varying TMS parameters affect targeted brain regions in order to optimize its impact on enhancing fear extinction memory consolidation in a population with known fear extinction deficiencies: post-traumatic stress disorder (PTSD). 250 subj…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Willing and able to provide informed consent.
* Inclusion Criteria for PTSD Subjects - Diagnosis of current PTSD
* Inclusion Criteria: Healthy Controls (HC) - no current psychiatric disorders ("Axis I" disorders)
Exclusion Criteria:
* Lifetime history of seizure or significa…
Contacts