No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
60 and older
Sex
Any
Study type
Observational
Participants needed
1,000 (estimated)
Sponsor
Vanderbilt University Medical Center · Other
Who this trial is looking for
This trial is looking for older adults aged 60 and up who may have Alzheimer's disease, mild cognitive impairment, or are cognitively unimpaired. Participants will be seen each year for assessments and may be referred to other studies related to Alzheimer's research.
Are You a Good Fit for This Trial?
You may be able to join if
I am 60 years old or older
I have mild cognitive impairment or Alzheimer's disease
I can speak English
You may not be able to join if
I do not have a reliable study partner
I have a history of major psychiatric illness
I have a history of major neurological illness
I have had a head injury with significant loss of consciousness
I am unable to undergo an MRI
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characterized and diverse clinical cohort, including participant referrals, biosamples, clinical data, and neuroimaging data. The VADRC Clinical Core will create an infrastructure to support research efforts of both local and national investigator s…
The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characterized and diverse clinical cohort, including participant referrals, biosamples, clinical data, and neuroimaging data. The VADRC Clinical Core will create an infrastructure to support research efforts of both local and national investigator studies to develop early detection, prevention, and treatment strategies for Alzheimer's disease. The Clinical Core intends to enroll up to 1000 participants, including individuals who are cognitively unimpaired, have mild cognitive impairment, or have Alzheimer's disease. This cohort of about 1000 participants will be called the Tennessee Alzheimer's Project. Participants will be seen annually for comprehensive clinical characterization and then referred to other studies to enhance Alzheimer's disease research activities.
Trial Locations
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City
State
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Status
Eligibility Criteria
Inclusion Criteria:
* Age 60 or older
* Meet standard criteria for (a) cognitively unimpaired, (b) mild cognitive impairment, or (c) Alzheimer's disease
* English speaking
* Individuals who lack decisional capacity to provide informed consent at baseline will not be enrolled in the study
Exclusion…
Inclusion Criteria:
* Age 60 or older
* Meet standard criteria for (a) cognitively unimpaired, (b) mild cognitive impairment, or (c) Alzheimer's disease
* English speaking
* Individuals who lack decisional capacity to provide informed consent at baseline will not be enrolled in the study
Exclusion Criteria:
* No available reliable study partner (reliable is defined as someone who interacts significantly with the participant and is available to participate in study visits in person or by phone)
* History of major psychiatric illness (e.g., schizophrenia, bipolar), neurological illness (e.g., epilepsy, multiple sclerosis, Parkinson's disease), or head injury with significant loss of consciousness.
* Unable to undergo MRI (e.g., claustrophobia, ferrous metal in body)
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