Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma

Recruiting Early Phase 1 Interventional Study
Newly Diagnosed Glioblastoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Early Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
10 (estimated)
Sponsor
Swedish Medical Center · Other
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About This Trial

Proposed treatment of subjects with newly diagnosed glioblastoma with novel personalized drug regimens identified to be effective in vitro using cancer stem cells derived from their individual tumors, alongside standard of care radiation and TMZ.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Histological diagnosis of GBM (WHO grade 4) * Subjects ≥18 years of age * Patients must have a life expectancy of \>6 months * Patients must have a surgically accessible tumor with the intent for a gross or near total resection of the tumor mass (GBM, WHO grade 4) * Patients m…
Contacts

Charles S Cobbs, M.D.

206-320-2300

charles.cobbs@swedish.org

CONTACT

Parvinder Hothi, Ph.D.

206-320-3145

parvinder.hothi@swedish.org

CONTACT