Newer Therapeutic Targets in Head and Neck Cancers
Recruiting
Observational Study
Head Neck Cancer
Oral Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 100
- Sex
- Any
- Study type
- Observational
- Participants needed
- 200 (estimated)
- Sponsor
- Banaras Hindu University · Other
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About This Trial
Based on the recently identified mutations in HNSCCs, the major pathologic pathways implicated in the tumorigenesis of HNSCC include dysregulation of four processes:
1. cellular survival and proliferation (e.g., TP53, EGFR, MET, and PIK3CA);
2. cell-cycle control (e.g., CDKN2A and CCND1);
3. cellular differentiation (e.g., NOTCH1); and
4. Adhesion and invasion signaling (e.g., FAT1).7 TP53, EGFR,…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Histologically proven cases of primary head and neck cancers.
Exclusion Criteria:
* Patients under 18 years of age
* Pregnant and lactating women
* Multiple cancers or patients with cancer of other sites.
Contacts