Sodium Lowering Vascular Effects Trial
Recruiting
N/A
Interventional Study
Endothelial Dysfunction
Vascular Stiffness
Left Ventricular Hypertrophy
Left Ventricular Dysfunction
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 40 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 256 (estimated)
- Sponsor
- Tulane University · Other
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About This Trial
The proposed mechanistic trial will test the effect of dietary sodium reduction on cardiac and vascular structure and function in those with elevated blood pressure or hypertension. Findings from this study will fill the knowledge gap on the underlying mechanisms of dietary sodium intake on cardiovascular disease risk in addition to blood pressure and could provide further evidence on sodium reduc…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Men or women aged ≥40 years. Individuals \<40 years are at a low risk for clinical and subclinical CVD
* Elevated BP or hypertension (systolic BP ≥120 mmHg and diastolic BP ≥80 mmHg with or without use of antihypertensive medications)
Exclusion Criteria:
* Glomerular filtrat…
Contacts