Remote Digital Physiologic Data Collection in Cancer: An MSK Registry Protocol

Inclusion Criteria: Project 1: HealthKit * Individuals who meet at least one of the following criteria: * Diagnosis of new onset early-stage (I-III), low-grade (I-II), or locally advanced solid tumor * Historical diagnosis of primary invasive solid tumor * Diagnosis of metastatic (stage IV) or high-grade (III-IV) disease * Enrolled onto an investigational trial in the EDD Service * Seen in the MSK UCC from 2021 and onwards * Completion of Survivorship Patient Self-Assessment * Adult without a history of cancer \<50 years of age * Adult without a history of cancer ≥ 50 years of age * ≥18 years old * Own an Apple iPhone or Android with valid operating software * Self-reported "very well" comprehension of written and verbal English language * Willing and able to provide informed consent and HIPAA authorization for the release of personal health information Project 2: DigIT-Ex Individuals who meet one of the following criteria: * Patients at MSK who are: * Scheduled to undergo any type of BMT (Cohort 1) * Diagnosed with new onset AML and scheduled to initiate antineoplastic therapy (Cohort 2) * Scheduled to undergo any surgery for prostate cancer (Cohort 3) * Scheduled to undergo any lung cancer surgery (Cohort 4) * Scheduled to undergo TNT for locally advanced rectal cancer (Cohort 5) * Scheduled to initiate androgen deprivation therapy for at least 12 months and has one of the following prostate cancer diagnoses (Cohort 6): * High risk/very high localized, locally advanced, * Biochemically recurrent prostate cancer * Treatment naïve, low-volume metastatic prostate cancer * Scheduled Scheduled to undergo chemotherapy for metastatic pancreatic cancer (Cohort 7) * Receiving outpatient care at Memorial Sloan Kettering Cancer Center (MSK)(Cohort 10) * Diagnosed with metastatic cancer to bone (Cohort 10) * Scheduled for non-emergent orthopaedic surgery to stabilize lower-extremity bone metastases (Cohort 10) * Able to undergo at least 5 consecutive days of preoperative monitoring prior to surgery (Cohort 10) * Have had a CT scan including the L3 vertebral level within 3 months before surgery (used to assess skeletal muscle mass and sarcopenia) (Cohort 10) * Have a ≥50% predicted likelihood of 6-month postoperative survival, as estimated by the PATHFx clinical decision-support tool (Cohort 10 * Individuals without cancer \<50 years of age (Cohort 8) * Individuals without cancer ≥50 years of age (Cohort 9) * 18 to 90 years old at the time of consent * Willing and able to download the Withings Health Mate app onto their personal mobile device * Willing to provide mobile digital physiological data for a period of at least six months to a maximum of one year following consent for Cohorts 1-9, and 4 months following consent for Cohort 10. * Willing to provide informed consent Exclusion Criteria: Project 1: HealthKit * Unable or unwilling to successfully export and /or share physiological data Project 2: DigIT-Ex * Unable or unwilling to appropriately use digital platforms or devices * Require a wheelchair for ambulation (Cohort 10) * Are undergoing stabilization surgery for a primary bone tumor (rather than metastatic disease) (Cohort 10)