Botulinum Toxin Therapy in Hidradenitis Suppurativa

Recruiting Observational Study
Hidradenitis Suppurativa Hyperhidrosis
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 75
Sex
Any
Study type
Observational
Participants needed
20 (estimated)
Sponsor
University of Massachusetts, Worcester · Other
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About This Trial

This study will build on data from mice and humans implicating TRPV1 nociceptors in the pathogenesis of the type-17 chronic inflammatory skin disease Hidradenitis Suppurativa (HS). In this study, the investigators will test the hypothesis that inhibiting neuropeptide activity with botulinum toxin reduces pathogenic inflammation.

Trial Locations
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Eligibility Criteria
Inclusion: * Adults between ages 18 and 75 years with established diagnosis of hidradenitis suppurativa (HS) * HS skin lesions of duration at least 1 year, HS skin lesions in at least two different body areas Exclusion: * Age \< 18 years or \> 75 years * pregnant or breastfeeding * neuromuscular …
Contacts

Sarah K Whitley, MD PhD

(508)856-4086

sarah.whitley@umassmed.edu

CONTACT

Deborah White, Deborah Peduzzi

(508)856-2664

deborah.white@umassmed.edu

CONTACT