Prediction of Postoperative Treatment Efficacy and Recurrence Risk of High-risk GIST Based on Liquid Biopsy MRD

Recruiting Observational Study
Gastrointestinal Stromal Tumors Minimal Residual Disease
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At a Glance
Sex
Any
Study type
Observational
Participants needed
45 (estimated)
Sponsor
Peking University People's Hospital · Other
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About This Trial
So far, MRD assessment by liquid biopsy (ctDNA) has not been used to predict postoperative treatment efficacy and recurrence risk of GIST patients because of special disease characteristics and technological limitations. Therefore, we conducted this prospective multi-center, single-arm observational study to collect 45 operable patients with locally advanced, suspected high-risk GIST. NGS genetic …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients aged between 18 and 80 * Patients suspected for high-risk GIST by preoperative imaging examinations or diagnosed with high-risk GIST by pathological biopsy, who have not received preoperative neoadjuvant treatment * Patients must have not received any treatment includ…
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