Investigating Lithium Levels for Bipolar and Depression
Basal Plasma Lithium Levels and Suicidal Events
Recruiting
Observational Study
Major Depressive Disorder
Suicidal Behavior
Bipolar Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 158 (estimated)
- Sponsor
- University Hospital, Montpellier · Other
Who this trial is looking for
This trial is looking for adults with major depression who may have experienced suicidal thoughts or attempts. Participants will help researchers understand the role of lithium levels in these conditions.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 18 years old or older
- I have a current major depressive episode
- I have not taken lithium in the past 12 months
- I have had a suicidal event in the past 12 months (if I'm a suicide attempter/ideator)
- I have not had a suicidal event in the past 12 months (if I'm an affective control)
You may not be able to join if
- I have a lifetime diagnosis of schizoaffective disorder, schizophrenia, or psychosis
- I am pregnant or breastfeeding
- I am currently incarcerated or detained
- I am under legal guardianship or curatorship
- I cannot understand the experimental procedures
- I am not affiliated with the French National Social Security System
- I do not consent to participate in the study
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Suicidal behavior is a major public health issue and there are currently no specific treatments for it.
However, lithium, the reference treatment for bipolar disorder, have been shown to be effective in preventing suicidal risk.
Apart from drug treatments, lithium is present in our environment and its levels varies from one individual to another, depending, especially, on diet.
Knowing that pat…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18 years old or over
* Current major depressive episode according to the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) criteria
* No lithium-based treatment over the last 12 months
* For suicide attempters/ideations only : suicidal event over the last 12 months…
Contacts