Natalizumab for the Treatment of People With Inflammatory Demyelination Suggestive of Multiple Sclerosis, or Definite Multiple Sclerosis, at First Presentation (AttackMS)

Recruiting Phase 2 Interventional Study
Multiple Sclerosis Clinically Isolated Syndrome of Demyelination
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 55
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
40 (estimated)
Sponsor
Queen Mary University of London · Other
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About This Trial
Multiple Sclerosis (MS) is a chronic inflammatory \& degenerative disease of the central nervous system (CNS) Recent data from the MS Base registry demonstrated an average delay of 152 - 215 days between first presentation and the diagnosis of MS, and more than one year until Disease Modifying Treatment (DMT) begins. Evidence suggests that shutting down inflammation using highly effective DMTs ea…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Participant has provided informed consent. 2. Age 18-55 years 3. Participant with CIS or MS at first presentation. 4. Participants show two or more lesions on T2 weighted MRI suggestive of demyelination. 5. Participant is willing and able to comply with clinical visits and pr…
Contacts

Klaus Schmierer

+44 20 7882 6246

k.schmierer@qmul.ac.uk

CONTACT

Julia Elizabeth Phillips

attackms@qmul.ac.uk

CONTACT