Risk Factors and Biomarkers for Post-tuberculosis Lung Damage
Recruiting
Observational Study
Pulmonary TB
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 25 – 60
- Sex
- Male
- Study type
- Observational
- Participants needed
- 400 (estimated)
- Sponsor
- Peking University Third Hospital · Other
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About This Trial
This prospective study aims to determine the incidence of Post-tuberculosis lung damage (PTLD), examine trends in the changes in lung function, and investigate the impact of smoking and other factors on respiratory symptoms, lung function, and chest CT findings, which will aid in the development of prognostic and therapeutic strategies for PTLD.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Male patients aged 25-60 years newly diagnosed with active pulmonary TB.
Exclusion Criteria:
1. patients with positive sputum smear or TB culture results;
2. human immunodeficiency virus-positive patients;
3. patients infected with multidrug-resistant TB;
4. patients with mali…