This longitudinal, prospective, multicentre study is to monitor lung function prospectively in childhood cancer patients after diagnosis. The impact of cancer treatment on pulmonary dysfunction non-invasively using lung function, lung imaging and breath analysis as well as clinical symptoms using a questionnaire will be assessed at different time points.
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Eligibility Criteria
Inclusion Criteria:
* at least one of the following cancer treatments:
* chest radiation
* treatment with any kind of chemotherapy
* hematopoietic stem cell transplantation (HSCT)
* thoracic surgery
* consent for Childhood Cancer Registry (ChCR) registration
Exclusion Criteria:
* no sign…
Inclusion Criteria:
* at least one of the following cancer treatments:
* chest radiation
* treatment with any kind of chemotherapy
* hematopoietic stem cell transplantation (HSCT)
* thoracic surgery
* consent for Childhood Cancer Registry (ChCR) registration
Exclusion Criteria:
* no signed informed consent
* Operation outside the chest area as only cancer treatment
* Relapsed cancer (patients who develop relapse during the study will not be excluded)
* In addition for MRI and lung function tests:
* Subjects who are respiratory insufficient and cannot perform a lung function test (less than 92% O2 saturation; under O2 therapy)
* Pregnant
* MRI measurement not possible without sedation
* Metal (e.g. pacemaker) in the body
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