iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH

Recruiting N/A Interventional Study
Pulmonary Hypertension
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
8 – 18
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
25 (estimated)
Sponsor
Children's Hospital of Philadelphia · Other
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About This Trial
Children with pulmonary hypertension (PH) engage in less physical activity than their peers. This is a concern since adult data support exercise as a non-pharmacologic treatment for PH. Despite adult data, therapeutic exercise has not been widely adopted in pediatric PH. Investigators have previously demonstrated that children with PH have less skeletal muscle mass in association with worse exerci…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 8-18 years * PH World Health Organization (WHO) diagnostic groups 1, 2, 3, or 4 (pulmonary arterial hypertension, PH due to left heart disease, PH due to lung disease, chronic thromboembolic PH) * WHO functional class I or II * Ambulatory status * Mean pulmonary to systemi…
Contacts

Catherine Avitabile, MD

215-590-4040

avitabilec@chop.edu

CONTACT