Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
Recruiting
Phase 2
Interventional Study
Mild Cognitive Impairment
Amnestic Mild Cognitive Disorder
Amnestic Mild Cognitive Impairment
Mild Traumatic Brain Injury
Concussion, Brain
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 55 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 75 (estimated)
- Sponsor
- University of Texas Southwestern Medical Center · Other
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About This Trial
This study will probe if the biological changes in amnestic mild cognitive impairment (aMCI) are related to a history of mild traumatic brain injury (mTBI) using high definition transcranial direct current stimulation (HD-tDCS) and blood-derived biomarker tools. Participants who Do as well as those who Do Not have a history of mTBI will be enrolled in the study.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Active diagnosis of amnestic mild cognitive impairment
2. Presence of an mTBI history for the mTBI+ group; absence of an mTBI history for a control sample
3. Female and male subjects
4. All races/ethnicities
5. Age 55 years and older
6. Fluent in English
Exclusion Criteria:
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Contacts