A Study on Predictive Models and Clinical Outcome of Radiation Pneumonitis
Recruiting
Observational Study
Radiation Pneumonitis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 300 (estimated)
- Sponsor
- Huazhong University of Science and Technology · Other
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About This Trial
Radiation pneumonitis is the main dose-limiting toxicity of thoracic radiotherapy, which can affect life quality, survival, and the tumor-controlling effects of patients receiving thoracic radiotherapy.
The purpose of this study is to:
* Identify biomarkers including serum proteins, gene expression, genetic changes, and epigenetic modifications that determine radiation pneumonitis.
* Investigate…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Clinical diagnosis of lung cancer by histology
2. Radiation dose at least 45 Gy
3. Karnofsky \>60
4. Age\>18
5. Life expectancy of at least 6 months
Exclusion Criteria:
1. Previous thoracic irradiation
2. Severe cardiopulmonary diseases
Contacts