Fluorine-18 Imaging for Non-Small Cell Lung Cancer

Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer

Recruiting Phase 1 Interventional Study
Lung Cancer Lung Cancer Metastatic Brain Metastases Non Small Cell Lung Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Diagnostic
Participants needed
20 (estimated)
Sponsor
University of California, Davis · Other
Who this trial is looking for

This trial is looking for adults with non-small cell lung cancer that has spread to the brain. Participants will undergo imaging scans to assess their condition using a specific imaging agent.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am over 18 years old.
  • I have been diagnosed with non-small cell lung cancer that has spread to the brain.
  • My doctor thinks I will live at least 3 more months.
  • I have tumor tissue available for testing.
  • I can stay still for up to 60 minutes during scans.
  • I can understand and sign a consent form.
  • I plan to receive additional cancer treatment soon.
  • I have had a PET/CT scan and an MRI of my brain within the last 21 days.

You may not be able to join if

  • I am pregnant or breastfeeding.
  • I am currently in prison.
  • I have another type of cancer that could interfere with the study.
  • I weigh more than 350 pounds.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

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About This Trial

This study investigates fluorine-18-AlphaVBeta6-BP (\[18F\]-αvβ6-BP) as a Positron Emission (PET) imaging agent in Non-Small Cell Lung Cancer (NSCLC) patients with brain metastases. Investigators hypothesize that \[18F\]-αvβ6-BP PET/Computed Tomography (CT) is a sensitive tool for disease assessment in patients with metastatic NSCLC, including those with brain metastases.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Men and women age \>18 yrs 2. Biopsy proven NSCLC with brain metastases (treated or untreated) 3. Life-expectancy of ≥3 months in the opinion of the treating physician 4. Available archival tumor tissue (excisional, core, or fine needle aspiration (FNA) is acceptable). Tissue…
Contacts

Principal Investigator

916-734-5536

jlsutcliffe@ucdavis.edu

CONTACT

Julie L Sutcliffe

9167345536

jlsutcliffe@ucdavis.edu

CONTACT