Neuroplasticity in RBD
Recruiting
N/A
Interventional Study
REM Sleep Behavior Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 21 – 75
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 86 (estimated)
- Sponsor
- University of Minnesota · Other
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About This Trial
REM sleep behavior disorder is a parasomnia that reflects the presence of alpha-synucleinopathy in the brain and is highly predictive of eventual phenoconversion to Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy over the course of years to decades. Neuroplastic adaptations in the brain during the prodromal stage of disease are thought to mask the expression of motor and…
Trial Locations
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Eligibility Criteria
Inclusion Criteria for the iRBD Group:
* Diagnosis of polysomnogram-confirmed isolated iRBD.
* Able to ambulate independently without the use of an assistive device (e.g., cane) for 50 meters.
* Age: 21-75 years.
Inclusion Criteria For Control Subject Group:
* Age: 21-75 years.
* Able to ambulate…
Contacts