Estimating Risk of Respiratory Infections Attributable to CFTR Heterozygosity

Recruiting Observational Study
Carrier State Respiratory Infections
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 100
Sex
Any
Study type
Observational
Participants needed
160 (estimated)
Sponsor
Philip Polgreen · Other
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About This Trial
A research team member will brush the inferior surface of the subjects' middle turbinate (nasal cavity) using a cytology brush to obtain the cells needed to perform our functional respiratory assays. An individual trained in phlebotomy will draw one 3 ml lavender top tube of blood to test c-reactive protein, calprotectin, and lactoferrin. They will also draw a 5 ml gold top serum separator tube o…
Trial Locations
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Eligibility Criteria
CF Carrier Inclusion Criteria: * Previously tested and shown to be a CF carrier * English-speaking Control Group Inclusion Criteria: * Previously tested and shown to not be a CF carrier or CF patient * English-speaking Exclusion Criteria: * Currently sick with a respiratory infection * Prisoner…
Contacts

Philip M Polgreen, MD

(319) 384-6194

philip-polgreen@uiowa.edu

CONTACT

Shelby L Francis, PhD

319-678-8037

shelby-francis@uiowa.edu

CONTACT